Clinical Research Sources

HOMEPAGE

1. Data on file.
2. Bullimore MA, Liu M. Efficacy of the Euclid orthokeratology lens in slowing axial elongation. Contact Lens and Anterior Eye. 2023;0(0). doi:10.1016/j.clae.2023.101875

PRODUCTS | DAILY MYOPIA LENSES

1. Data on file.

2. Smith III EL, Arumugam B, Hung LF, She Z, Beach K, Sankaridurg P. Eccentricity-dependent effects of simultaneous competing defocus on emmetropization in infant rhesus monkeys. Vision Research. 2020;177:32-40.

3. Smith EL, Hung LF, Huang J. Relative peripheral hyperopic defocus alters central refractive development in infant monkeys. Vision Res. 2009;49(19):2386-2392.

PRODUCTS | ORTHO-K LENSES

1. Bullimore MA, Liu M. Efficacy of the Euclid orthokeratology lens in slowing axial elongation. Contact Lens and Anterior Eye. 2023;0(0). doi:10.1016/j.clae.2023.101875

2. Cooper J, Aller T, Smith EL, Chan K, Dillehay SM, O’Connor B. Retrospective Analysis of a Clinical Algorithm for Managing Childhood Myopia Progression. Optom Vis Sci. 2023;100(1):117-124.

3. Data on file.

*Minimal is defined as less than or equal to 0.25D or 0.10 mm per year.

**Information retrieved from a survey on 50 patients; data on file.

PRODUCTS | ORTHO-K LENSES FAQs

1. Davis, R. L., S. B. Eiden, E. S. Bennett, B. Koffler, L. Wohl, and M. Lipson. “Stabilizing Myopia by Accelerating Reshaping Technique (SMART)-Study Three Year Outcomes and Overview.” Advances in Ophthalmology & Visual System 2, no. 3 (2015): 8.

2. Mika, R, B Morgan, M Cron, J Lotoczky, and J Pole. “Safety and Efficacy of Overnight Orthokeratology in Myopic Children.” Optometry: Journal of the American Optometric Association 78, no. 5 (2007): 225-31. https://doi.org/10.1016/j.optm.2006.12.013.

3. Bullimore, M, L Sinnott, and L Jones-Jordan. “The Risk of Microbial Keratitis With Overnight Corneal Reshaping Lenses.” Optometry & Vision Science 90, no. 9 (2013): 937-44. https://doi.org/10.1097/opx.0b013e31829cac92.

4. Liu, Yue M., and Peiying Xie. “The Safety of Orthokeratology—A Systematic Review:” Eye & Contact Lens: Science & Clinical Practice 42, no. 1 (January 2016): 35-42. https://doi.org/10.1097/ICL.0000000000000219.

5. Santodomingo-Rubido, Jacinto, César Villa-Collar, Bernard Gilmartin, and Ramón Gutiérrez-Ortega. “Orthokeratology vs. Spectacles: Adverse Events and Discontinuations.” Optometry & Vision Science 89, no. 8 (2012): 1133-1139.

6. Van Meter, W, D Musch, D Jacobs, S Kaufman, W Reinhart, and I Udell. “Safety of Overnight Orthokeratology for Myopia.” Ophthalmology 115, no. 12 (2008): 2301-13. https://doi.org/10.1016/j.ophtha.2008.06.034.

7. Walline, J, M Rah, and L Jones. “COOKI: The Children’s Overnight Orthokeratology Investigation Pilot Study.” Optometry & Vision Science 81, no. 6 (2004): 407-13. https://doi.org/10.1097/01.opx.0000135093.77007.18.

8. Santodomingo-Rubido, Jacinto, César Villa-Collar, Bernard Gilmartin, and Ramón Gutiérrez-Ortega. “Short-Term Changes in Ocular Biometry and Refraction After Discontinuation of Long-Term Orthokeratology:” Eye & Contact Lens: Science & Clinical Practice 40, no. 2 (March 2014): 84–90. https://doi.org/10.1097/ICL.0000000000000014.

9. Bullimore MA, Liu M. Efficacy of the Euclid orthokeratology lens in slowing axial elongation. Contact Lens and Anterior Eye. 2023;0(0).

10. Charm, Jessie, and Pauline Cho. “High Myopia–Partial Reduction Ortho-k: A 2-Year Randomized Study.” Optometry & Vision Science 90, no. 6 (2013): 530-539.

11. Chen, Connie, Sin Wan Cheung, and Pauline Cho. “Myopia Control Using Toric Orthokeratology (TO-SEE Study).” Investigative Opthalmology & Visual Science 54, no. 10 (October 3, 2013): 6510. https://doi.org/10.1167/iovs.13-12527.

12. Cho, Pauline, and Sin-Wan Cheung. “Protective Role of Orthokeratology in Reducing Risk of Rapid Axial Elongation: A Reanalysis of Data From the ROMIO and TO-SEE Studies.” Investigative Opthalmology & Visual Science 58, no. 3 (March 2, 2017): 1411. https://doi.org/10.1167/iovs.16-20594.

13. Cho, P and Cheung, S. “Retardation of Myopia in Orthokeratology (ROMIO) Study: A 2-Year Randomized Clinical Trial.” Investigative Opthalmology & Visual Science 53, no. 11 (October 11, 2012): 7077. https://doi.org/10.1167/iovs.12-10565.

14. Downie, Laura E., and Russell Lowe. “Corneal Reshaping Influences Myopic Prescription Stability (CRIMPS): An Analysis of the Effect of Orthokeratology on Childhood Myopic Refractive Stability.” Eye & Contact Lens: Science & Clinical Practice 39, no. 4 (July 2013): 303-10. https://doi.org/10.1097/ICL.0b013e318298ee76.

15. He, Mengmei, Yaru Du, Qingyu Liu, Chengda Ren, Junling Liu, Qianyi Wang, Li Li, and Jing Yu. “Effects of Orthokeratology on the Progression of Low to Moderate Myopia in Chinese Children.” BMC Ophthalmology 16, no. 1 (December 2016). https://doi.org/10.1186/s12886-016-0302-5.

16. Hiraoka, Takahiro, Tetsuhiko Kakita, Fumiki Okamoto, Hideto Takahashi, and Tetsuro Oshika. “Long-Term Effect of Overnight Orthokeratology on Axial Length Elongation in Childhood Myopia: A 5-Year Follow-Up Study.” Investigative Opthalmology & Visual Science 53, no. 7 (June 25, 2012): 3913. https://doi.org/10.1167/iovs.11-8453.

17. Mok, Alan. “Seven-Year Retrospective Analysis of the Myopic Control Effect of Orthokeratology in Children: A Pilot Study.” Clinical Optometry, February 2011, 1. https://doi.org/10.2147/OPTO.S16599.

18. Santodomingo-Rubido, Jacinto, César Villa-Collar, Bernard Gilmartin, and Ramón Gutiérrez-Ortega. “Myopia Control with Orthokeratology Contact Lenses in Spain: Refractive and Biometric Changes.” Investigative Opthalmology & Visual Science 53, no. 8 (July 31, 2012): 5060. https://doi.org/10.1167/iovs.11-8005.

19. Zhu, M, H Feng, X He, H Zou, and J Zhu. “The Control Effect of Orthokeratology on Axial Length Elongation in Chinese Children with Myopia.” BMC Ophthalmology 14, no. 1 (2014): 141. https://doi.org/10.1186/1471-2415-14-141.

20. González-Méijome, José M., Sofia C. Peixoto-de-Matos, Miguel Faria-Ribeiro, Daniela P. Lopes-Ferreira, Jorge Jorge, Jerry Legerton, and Antonio Queiros. “Strategies to Regulate Myopia Progression With Contact Lenses: A Review.” Eye & Contact Lens: Science & Clinical Practice 42, no. 1 (January 2016): 24-34. https://doi.org/10.1097/ICL.0000000000000100.

21. Huang, J, D Wen, and Q Wang. “Efficacy Comparison of 16 Interventions for Myopia Control in Children.” Ophthalmology 123, no. 4 (2016): 697-708. https://doi.org/10.1016/j.ophtha.2015.11.010.

22. Walline, Jeffrey J. “Myopia Control: A Review.” Eye & Contact Lens: Science & Clinical Practice 42, no. 1 (January 2016): 3-8. https://doi.org/10.1097/ICL.0000000000000207.

23. Wen, D, J Huang, and H Chen. “Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis.” Journal of Ophthalmology, 2015, 1-12. https://doi.org/10.1155/2015/360806.

PRODUCTS | MEDMONT MERIDIA CORNEAL TOPOGRAPHER

*Using KATT BE Free Ortho-K designs in Hong-Kong Studies: Tan 2019, Orthokeratology, Guo 2021, Orthokeratology

YOUR PRACTICE | MYOPIA EPIDEMIC

1. Holden BA, Fricke TR, Wilson DA, Jong M, Naidoo KS, Sankaridurg P, Wong TY, Naduvilath TJ, Resnikoff S. Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050. Ophthalmology. May 2016;123(5):1036–1042.

2. Vitale S, Sperduto RD, Ferris FL, 3rd. Increased Prevalence of Myopia in the U.S. between 1971-1972 and 1999-2004. Arch Ophthalmol. 2009 Dec;127(12):1632-9.

3. Morgan, I.G., Ohno-Matsui, K., and Saw, S.M. Myopia. Lancet. 2012; 379: 1739–1748

4. Mitchell P, Hourihan F, Sandbach J, Wang JJ. The relationship between glaucoma and myopia: the Blue Mountains Eye Study. Ophthalmology. 1999;106:2010-5.

5. Younan C, Mitchell P, Cumming RG, Rochtchina E, Wang JJ. Myopia and incident cataract and cataract surgery: The BlueMountains eye study. Investigative ophthalmology & visual science 2002;43:3625-32.

6. Group TEDC-CS. Risk factors for idiopathic rhegmatogenous retinal detachment. The Eye Disease Case-Control Study Group. American Journal of Epidemiology 1993;137:749-57.

YOUR PRACTICE | YOUR PRACTICE

1.Hale L, Guan S. Screen time and sleep among school-aged children and adolescents: A systematic literature review. Sleep Med Rev. 2015;21:50-58. doi:10.1016/j.smrv.2014.07.007

PATIENTS | MYOPIA EXPLAINED

1. Wong TY, Ferreira A, Hughes R, Carter G, Mitchell P. Epidemiology and disease burden of pathologic myopia and myopic choroidal neovascularization: an evidence-based systematic review. Am J Ophthalmol. 2014;157:9–25.

2. Holden BA, Fricke TR, Wilson DA, Jong M, Naidoo KS, Sankaridurg P, Wong TY, Naduvilath TJ, Resnikoff S. Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050. Ophthalmology. May 2016;123(5):1036–1042.

3. Morgan IG, Ohno-Matsui K, Saw SM. Myopia. Lancet. 2012;379:1739-48.

4. Vitale S, Sperduto RD, Ferris FL, 3rd. Increased Prevalence of Myopia in the U.S. between 1971-1972 and 1999-2004. Arch Ophthalmol. 2009 Dec;127(12):1632-9.

PATIENT | ORTHO-K LENSES FAQs

1. Davis, R. L., S. B. Eiden, S.B., E. S. Bennett, B. Koffler, L. Wohl, and M. Lipson. “Stabilizing Myopia by Accelerating Reshaping Technique (SMART)-Study Three Year Outcomes and Overview.” Advances in Ophthalmology & Visual System 2, no. 3 (2015): 8.

9. Charm, Jessie, and Pauline Cho. “High Myopia–Partial Reduction Ortho-k: A 2-Year Randomized Study.” Optometry & Vision Science 90, no. 6 (2013): 530-539.

10. Chen, Connie, Sin Wan Cheung, and Pauline Cho. “Myopia Control Using Toric Orthokeratology (TO-SEE Study).” Investigative Opthalmology & Visual Science 54, no. 10 (October 3, 2013): 6510. https://doi.org/10.1167/iovs.13-12527.

11. Cho, Pauline, and Sin-Wan Cheung. “Protective Role of Orthokeratology in Reducing Risk of Rapid Axial Elongation: A Reanalysis of Data From the ROMIO and TO-SEE Studies.” Investigative Opthalmology & Visual Science 58, no. 3 (March 2, 2017): 1411. https://doi.org/10.1167/iovs.16-20594.

12. Cho, P and Cheung, S. “Retardation of Myopia in Orthokeratology (ROMIO) Study: A 2-Year Randomized Clinical Trial.” Investigative Opthalmology & Visual Science 53, no. 11 (October 11, 2012): 7077. https://doi.org/10.1167/iovs.12-10565.

13. Downie, Laura E., and Russell Lowe. “Corneal Reshaping Influences Myopic Prescription Stability (CRIMPS): An Analysis of the Effect of Orthokeratology on Childhood Myopic Refractive Stability.” Eye & Contact Lens: Science & Clinical Practice 39, no. 4 (July 2013): 303-10. https://doi.org/10.1097/ICL.0b013e318298ee76.

14. He, Mengmei, Yaru Du, Qingyu Liu, Chengda Ren, Junling Liu, Qianyi Wang, Li Li, and Jing Yu. “Effects of Orthokeratology on the Progression of Low to Moderate Myopia in Chinese Children.” BMC Ophthalmology 16, no. 1 (December 2016). https://doi.org/10.1186/s12886-016-0302-5.

15. Hiraoka, Takahiro, Tetsuhiko Kakita, Fumiki Okamoto, Hideto Takahashi, and Tetsuro Oshika. “Long-Term Effect of Overnight Orthokeratology on Axial Length Elongation in Childhood Myopia: A 5-Year Follow-Up Study.” Investigative Opthalmology & Visual Science 53, no. 7 (June 25, 2012): 3913. https://doi.org/10.1167/iovs.11-8453.

16. Mok, Alan. “Seven-Year Retrospective Analysis of the Myopic Control Effect of Orthokeratology in Children: A Pilot Study.” Clinical Optometry, February 2011, 1. https://doi.org/10.2147/OPTO.S16599.

17. Santodomingo-Rubido, Jacinto, César Villa-Collar, Bernard Gilmartin, and Ramón Gutiérrez-Ortega. “Myopia Control with Orthokeratology Contact Lenses in Spain: Refractive and Biometric Changes.” Investigative Opthalmology & Visual Science 53, no. 8 (July 31, 2012): 5060. https://doi.org/10.1167/iovs.11-8005.

18. Zhu, M, H Feng, X He, H Zou, and J Zhu. “The Control Effect of Orthokeratology on Axial Length Elongation in Chinese Children with Myopia.” BMC Ophthalmology 14, no. 1 (2014): 141. https://doi.org/10.1186/1471-2415-14-141.

19. González-Méijome, José M., Sofia C. Peixoto-de-Matos, Miguel Faria-Ribeiro, Daniela P. Lopes-Ferreira, Jorge Jorge, Jerry Legerton, and Antonio Queiros. “Strategies to Regulate Myopia Progression With Contact Lenses: A Review.” Eye & Contact Lens: Science & Clinical Practice 42, no. 1 (January 2016): 24-34. https://doi.org/10.1097/ICL.0000000000000100.

20. Huang, J, D Wen, and Q Wang. “Efficacy Comparison of 16 Interventions for Myopia Control in Children.” Ophthalmology 123, no. 4 (2016): 697-708. https://doi.org/10.1016/j.ophtha.2015.11.010.

21. Walline, Jeffrey J. “Myopia Control: A Review.” Eye & Contact Lens: Science & Clinical Practice 42, no. 1 (January 2016): 3-8. https://doi.org/10.1097/ICL.0000000000000207.

22. Wen, D, J Huang, and H Chen. “Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis.” Journal of Ophthalmology, 2015, 1-12. https://doi.org/10.1155/2015/360806.

23. Bullimore, M., and L. Johnson. “Overnight Orthokeratology.” Contact Lens and Anterior Eye, 43 (2020): 322-332.

24. Euclid Systems Orthokeratology Contact Lenses for Overnight Wear – Instructions for Use.